Neurophysiological studies of visual search in monkeys have demonstrated how the visual salience map is distributed across a network of sensory-motor structures that include the lateral intraparietal (LIP) area (Ipata et al., 2006; Thomas and Paré, 2007), the frontal eye field (FEF; Thompson et al., 1996; Thompson and Bichot, 2005), as well as the superior colliculus (SC; McPeek and Keller, 2002; Shen and Paré, 2007; Shen et al., 2011). These neurons give visually evoked responses to stimuli falling in their receptive fields and subsequently signal the location of the saccade target before saccades are made. Neurons in area LIP and FEF are also influenced by prior information, showing feature-based modulations that are task-relevant (Bichot and Schall, 1999a; Toth and Assad, 2002) as well as memory-related (Bichot and Schall, 1999a), i.e., priming of distracter stimuli whose features were those of the target in the previous search session.
The evidence presented in this paper for feature-based contextual modulation in the activity of SC sensory-motor neurons adds further support to the hypothesis that the SC instantiates the visual salience map postulated by models of visual search and selective attention (Cave and Wolfe, 1990; Findlay and Walker, 1999; Itti and Koch, 2000; Glimcher et al., 2005; Hamker, 2006). According to these models, the stimulus-driven outputs from individual feature maps, which can be instantiated by extra-striate cortical areas, are integrated with goal-directed signals into the visual salience map. Previous studies have shown how SC neurons have stimulus-driven visual responses to targets and distracters in their receptive fields and that their activity evolves to reflect the selection of saccade goals (McPeek and Keller, 2002). SC also has stimulus representations whose magnitudes are predictive of which stimulus will be selected as a saccade target (Shen and Paré, 2007). The present study extends these findings further by demonstrating how SC stimulus representations are also modulated by recent history as well as by visual context.
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